In Ali Smith's wonderful book Artful (2013), based on a series of lectures she gave at Oxford, which combines fiction and the essay form in an astonishing and complex discussion of art and storytelling, she writes the following

I share this for two reasons. First, because it is emblematic of her cast of mind, of her subtle understanding of complexities, of her grasp of both art and the human heart, and of her humor. Second, to grieve. I know her idea to be correct, and at my age (late-middle) I grieve that I will have fewer opportunities than lucky younger readers, to re-appreciate and wonder at each repeat read of her new novel, Autumn.
Smith wrote it last summer after the Brexit vote in the UK. Autumn, which travels back and forth through time, has a feisty anger in its present-day scenes. People for or against Brexit are stunned and wonder what the future might hold. It is an understatement to say it resonates here as well. But the politics, ripe as they are, play a minor roll.
This is a book about an unusual and profoundly tender friendship between 32-year-old (in the present scenes) Elisabeth, and Daniel, her former next-door neighbor and sometime babysitter, who in the present scenes is 101. It is a book of memory, forgetting, music, art history, love, family, poverty, a book about so many things, but always about connection and a hunger for life whatever it might have in store for each of us.
As it slides through time and we learn bits of each person's story, their disappointments, their tiny triumphs, the unbearable richness of each and any life rises up and catches our hearts over and over. Sad, funny, informative, insightful and deeply moving, it is an astonishing achievement. It is the beginning of a planned quartet of novels named for the seasons. It is difficult to imagine the other seasons having the abundance of Autumn, but I can hardly wait to find out.